Treatment

Preventing Bleeding During Chemotherapy

Choose a preferred language

Chemotherapy can make your blood less able to clot. This is because it lowers the number of clotting cells (platelets) in your blood. As a result, your risk of bruising and bleeding goes up. To help prevent problem bleeding, use the tips on this handout.


Know what to expect

Some types of chemotherapy cause more bleeding problems than others. Your risk of bleeding increases over the course of treatment. Your risk is greatest during the period in each treatment cycle when your platelet count is lowest. This is called the nadir. Talk with your healthcare provider about your nadir. Then take extra care to prevent bleeding at that time.


Preventing bleeding and bruising

  • When brushing your teeth, use a soft toothbrush. If flossing or using a dental water jet causes bleeding, stop until your platelet count increases.

  • Talk to your dentist about postponing teeth cleanings or dental work.

  • Shave with an electric razor, not a straight razor.

  • Ask your healthcare provider which medicines you should stop taking. Anti-inflammatory medicines such as aspirin, naproxen, or ibuprofen make it harder for blood to clot. Talk with your healthcare provider about all the medicines you take. This includes over-the-counter medicines, vitamins, supplements, and herbs.

  • Eat a high-fiber diet or take a stool softener to prevent constipation. Straining at stool can cause bleeding in your anus.

  • Don't do contact sports or other activities likely to cause bruising.

  • Don't use tampons, suppositories, or enemas.

  • Protect your skin from cuts, scrapes, and sharp objects.

  • Don't blow your nose or cough with great force.

  • Keep your home safe to prevent injuries and falls.


When to call your healthcare provider

Call your healthcare provider right away if you have:

  • Blood in your urine or stool

  • Easy bruising 

  • Small red spots under your skin

  • Bleeding that won’t stop, such as from your gums or nose

  • Menstrual flow that is heavy or lasts longer than normal

  • Vomiting

  • Vision changes

  • Frequent headaches

Featured in

Online Medical Reviewer: L Renee Watson MSN RN

Online Medical Reviewer: Rita Sather RN

Online Medical Reviewer: Todd Gersten MD

Date Last Reviewed: 12/01/2021

© 2000-2025 The StayWell Company, LLC. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.
doctor icon

Find the right provider to meet your needs

From primary care to specialty services and more.

Find a Doctor
appointment clock icon

Call for an Appointment

Offering personalized care at more than 20 clinics across three cities and two states.

Call Now
Related Articles
Read article
Oncology
Treating Bladder Cancer: Intravesical Therapy

Some types of bladder tumors are hard to remove completely with surgery. In certain cases, special medicines that kill cancer cells may be put right inside the bladder. This is called intravesical therapy. Read on to learn more.

Read article
Oncology
Radiation Therapy: Your Daily Life

Radiation therapy can help you in your fight against cancer. To feel better, get plenty of rest, exercise, and eat well. This will give your body the extra strength it needs right now. Also look to family and friends for support and comfort.

Read article
Oncology
External Beam Radiation Therapy: Understanding Your Treatment and Care

Radiation therapy is a treatment for cancer. It uses targeted high-energy X-rays or particles to destroy cancer cells.

Read article
Oncology
Radiation Therapy: Support and Resources

Use these resources to help you learn about radiation therapy.